impaired glucose tolerance_Gck<tm1.1Mgn>/Gck<+>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6DBA2Gcktm11MgnGckTgIns2cre25Mgn0GckTgIns2cre25MgnGcktm11Mgn

impaired glucose tolerance_Gck<tm1.1Mgn>/Gck<+>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• glucokinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270854

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gck<tm1.1Mgn>/Gck<+>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gck<+>|Tg(Ins2-cre)25Mgn|Gck<tm1.1Mgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• C. Postic, et.al., Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/9867845