impaired glucose tolerance_Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6GtROSA26Sortm3H1tetORNAiMir143JcbrGtROSA26SorGtROSA26SorGtROSA26Sortm3H1tetORNAiMir143Jcbr

impaired glucose tolerance_Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• Sabine D. Jordan, et.al., Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism., Nature cell biology, 2011, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/21441927