Sabine D. Jordan, et.al., Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism., Nature cell biology, 2011, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/21441927

Sabine D. Jordan, et.al., Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism., Nature cell biology, 2011, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(H1/tetO-RNAi:lacZ)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290086
• Gt(ROSA)26Sor<tm4(H1/tetO-RNAi:Mir145)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290084
• Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290071

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(H1/tetO-RNAi:lacZ)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290086
• Gt(ROSA)26Sor<tm4(H1/tetO-RNAi:Mir145)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290084
• Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5290071

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased insulin sensitivity_Mirc32<tm1Thbr>/Mirc32<tm1Thbr>
  http://metadb.riken.jp/0002891I129SvMirc32tm1ThbrMirc32tm1ThbrMirc32tm1Thbr
• increased circulating insulin level_Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002079I129S6SvEvTacC57BL6GtROSA26Sortm3H1tetORNAiMir143JcbrGtROSA26SorGtROSA26SorGtROSA26Sortm3H1tetORNAiMir143Jcbr
• improved glucose tolerance_Mirc32<tm1Thbr>/Mirc32<tm1Thbr>
  http://metadb.riken.jp/0005292I129SvMirc32tm1ThbrMirc32tm1ThbrMirc32tm1Thbr
• insulin resistance_Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005331I129S6SvEvTacC57BL6GtROSA26Sortm3H1tetORNAiMir143JcbrGtROSA26SorGtROSA26SorGtROSA26Sortm3H1tetORNAiMir143Jcbr
• impaired glucose tolerance_Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6GtROSA26Sortm3H1tetORNAiMir143JcbrGtROSA26SorGtROSA26SorGtROSA26Sortm3H1tetORNAiMir143Jcbr