abnormal heart ventricle morphology_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>

http://metadb.riken.jp/0005294I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc

abnormal heart ventricle morphology_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myosin, light polypeptide 2, regulatory, cardiac, slow
  http://metadb.riken.jp/db/mgi_rdf/MGI:97272
• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb1<tm1Ross>|Myl2<+>|Myl2<tm1(cre)Krc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal heart ventricle morphology
  http://purl.obolibrary.org/obo/MP_0005294

文献

http://purl.org/net/cito/citesAsAuthority

• Shaw-Yung. Shai, et.al., Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure., Circulation research, 2002, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/11884376