abnormal enzyme/coenzyme level_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Hprt<tm1(CMV-cre)Brd>/Hprt<+>,Nf1<tm1Fcr>/Nf1<tm1Fcr>

http://metadb.riken.jp/0005319I129SSvEv129SSvEvBrdGtROSA26Sortm1FiaGtROSA26SorHprttm1CMVcreBrdHprtNf1tm1FcrNf1tm1FcrGtROSA26Sortm1FiaHprttm1CMVcreBrdNf1tm1FcrGtROSA26SorHprt

abnormal enzyme/coenzyme level_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Hprt<tm1(CMV-cre)Brd>/Hprt<+>,Nf1<tm1Fcr>/Nf1<tm1Fcr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• hypoxanthine guanine phosphoribosyl transferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96217
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Hprt<tm1(CMV-cre)Brd>/Hprt<+>,Nf1<tm1Fcr>/Nf1<tm1Fcr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1Fia>|Hprt<tm1(CMV-cre)Brd>|Nf1<tm1Fcr>|Gt(ROSA)26Sor<+>|Hprt<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enzyme/ coenzyme level
  http://purl.obolibrary.org/obo/MP_0005319

文献

http://purl.org/net/cito/citesAsAuthority

• Fraz A. Ismat, et.al., The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice., The Journal of clinical investigation, 2006, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/16906226