abnormal renal glomerulus morphology_Cfb<tm1Hrc>/Cfb<+>,Cfh<tm1Mbo>/Cfh<tm1Mbo>

http://metadb.riken.jp/0005325I129SSvC57BL6Cfbtm1HrcCfbCfhtm1MboCfhtm1MboCfbtm1HrcCfbCfhtm1Mbo

abnormal renal glomerulus morphology_Cfb<tm1Hrc>/Cfb<+>,Cfh<tm1Mbo>/Cfh<tm1Mbo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• complement factor B
  http://metadb.riken.jp/db/mgi_rdf/MGI:105975
• complement component factor h
  http://metadb.riken.jp/db/mgi_rdf/MGI:88385

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cfb<tm1Hrc>/Cfb<+>,Cfh<tm1Mbo>/Cfh<tm1Mbo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cfb<tm1Hrc>|Cfb<+>|Cfh<tm1Mbo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal glomerulus morphology
  http://purl.obolibrary.org/obo/MP_0005325

文献

http://purl.org/net/cito/citesAsAuthority

• Matthew C. Pickering, et.al., Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H., Nature genetics, 2002, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12091909