Matthew C. Pickering, et.al., Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H., Nature genetics, 2002, 31

http://rdf.ncbi.nlm.nih.gov/pubmed/12091909

Matthew C. Pickering, et.al., Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H., Nature genetics, 2002, 31

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cfh<tm1Mbo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384179

class

http://purl.org/net/cito/citesAsAuthority

• Cfh<tm1Mbo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384179

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circulating protein level_Cfb<tm1Hrc>/Cfb<+>,Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005416I129SSvC57BL6Cfbtm1HrcCfbCfhtm1MboCfhtm1MboCfbtm1HrcCfbCfhtm1Mbo
• hematuria_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005161I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• increased urine protein level_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0002962I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• abnormal renal glomerulus basement membrane morphology_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0011348I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• expanded mesangial matrix_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0011353I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• increased susceptibility to type III hypersensitivity reaction_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005615I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• abnormal circulating protein level_Cfh<tm1Mbo>/Cfh<+>
  http://metadb.riken.jp/0005416I129SvC57BL6Cfhtm1MboCfhCfhCfhtm1Mbo
• abnormal circulating protein level_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005416I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• mesangial cell hyperplasia_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0011427I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• glomerulonephritis_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0002743I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• abnormal kidney capillary morphology_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0011310I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• albuminuria_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0002871I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• abnormal renal glomerulus morphology_Cfb<tm1Hrc>/Cfb<+>,Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005325I129SSvC57BL6Cfbtm1HrcCfbCfhtm1MboCfhtm1MboCfbtm1HrcCfbCfhtm1Mbo
• no abnormal phenotype detected_Cfb<tm1Hrc>/Cfb<tm1Hrc>,Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0002169I129SSvC57BL6Cfbtm1HrcCfbtm1HrcCfhtm1MboCfhtm1MboCfhtm1MboCfbtm1Hrc
• mesangial cell interposition_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0011512I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• premature death_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0002083I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo
• abnormal renal glomerulus morphology_Cfh<tm1Mbo>/Cfh<tm1Mbo>
  http://metadb.riken.jp/0005325I129SvC57BL6Cfhtm1MboCfhtm1MboCfhtm1Mbo