increased T cell proliferation_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm1(ITK/SYK)Jrld>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0005348I129P2OlaHsdCd19tm1creCgnCd19GtROSA26Sortm1ITKSYKJrldGtROSA26SorCd19tm1creCgnGtROSA26Sortm1ITKSYKJrldCd19GtROSA26Sor

increased T cell proliferation_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm1(ITK/SYK)Jrld>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm1(ITK/SYK)Jrld>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Gt(ROSA)26Sor<tm1(ITK/SYK)Jrld>|Cd19<+>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005348

文献

http://purl.org/net/cito/citesAsAuthority

• Konstanze. Pechloff, et.al., The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20439541