decreased susceptibility to prion infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*S170N*N174T)1020Aag/0

http://metadb.riken.jp/0005363I129S7SvEvBrdC57BL6Prnptm1CwePrnptm1CweTgPrnpS170NN174T1020Aag0Prnptm1CweTgPrnpS170NN174T1020Aag

decreased susceptibility to prion infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*S170N*N174T)1020Aag/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769
• transgene insertion 1020, Adriano Aguzzi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5569538

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*S170N*N174T)1020Aag/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prnp<tm1Cwe>|Tg(Prnp*S170N*N174T)1020Aag

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to prion infection
  http://purl.obolibrary.org/obo/MP_0005363

文献

http://purl.org/net/cito/citesAsAuthority

• Christina J. Sigurdson, et.al., De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19073920