abnormal food intake_Hsd11b1<tm1.2Awhi>/Hsd11b1<tm1.2Awhi>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0005449I129S1Sv129X1SvJC57BL6SJLHsd11b1tm12AwhiHsd11b1tm12AwhiTgNescre1Kln0TgNescre1KlnHsd11b1tm12Awhi

abnormal food intake_Hsd11b1<tm1.2Awhi>/Hsd11b1<tm1.2Awhi>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• hydroxysteroid 11-beta dehydrogenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103562

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hsd11b1<tm1.2Awhi>/Hsd11b1<tm1.2Awhi>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Hsd11b1<tm1.2Awhi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal food intake
  http://purl.obolibrary.org/obo/MP_0005449

文献

http://purl.org/net/cito/citesAsAuthority

• Erika. Harno, et.al., 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms., Endocrinology, 2013, 154
  http://rdf.ncbi.nlm.nih.gov/pubmed/24169553