Erika. Harno, et.al., 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms., Endocrinology, 2013, 154

http://rdf.ncbi.nlm.nih.gov/pubmed/24169553

Erika. Harno, et.al., 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms., Endocrinology, 2013, 154

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hsd11b1<tm1.2Awhi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5566778
• Hsd11b1<tm1.1Awhi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5566777

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased mesenteric fat pad weight_Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009299IC57BL6SJLTgNescre1Kln0TgNescre1Kln
• increased insulin sensitivity_Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002891IC57BL6SJLTgNescre1Kln0TgNescre1Kln
• abnormal food intake_Hsd11b1<tm1.2Awhi>/Hsd11b1<tm1.2Awhi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005449I129S1Sv129X1SvJC57BL6SJLHsd11b1tm12AwhiHsd11b1tm12AwhiTgNescre1Kln0TgNescre1KlnHsd11b1tm12Awhi
• decreased food intake_Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011940IC57BL6SJLTgNescre1Kln0TgNescre1Kln
• decreased body weight_Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262IC57BL6SJLTgNescre1Kln0TgNescre1Kln
• increased food intake_Hsd11b1<tm1.1Awhi>/Hsd11b1<tm1.1Awhi>
  http://metadb.riken.jp/0011939I129S1Sv129X1SvJC57BL6Hsd11b1tm11AwhiHsd11b1tm11AwhiHsd11b1tm11Awhi

class

http://purl.org/net/cito/citesAsAuthority

• Hsd11b1<tm1.2Awhi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5566778
• Hsd11b1<tm1.1Awhi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5566777