bronchial epithelial hyperplasia_Gt(ROSA)26Sor<tm1(CAG-Sox2,-EGFP)Blh>/Gt(ROSA)26Sor<+>,Tg(Sftpc-cre)1Blh/0

http://metadb.riken.jp/0005488I129SSvEvC57BL6DBA2GtROSA26Sortm1CAGSox2EGFPBlhGtROSA26SorTgSftpccre1Blh0GtROSA26SorGtROSA26Sortm1CAGSox2EGFPBlhTgSftpccre1Blh

bronchial epithelial hyperplasia_Gt(ROSA)26Sor<tm1(CAG-Sox2,-EGFP)Blh>/Gt(ROSA)26Sor<+>,Tg(Sftpc-cre)1Blh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Brigid L Hogan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3574944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-Sox2,-EGFP)Blh>/Gt(ROSA)26Sor<+>,Tg(Sftpc-cre)1Blh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(CAG-Sox2,-EGFP)Blh>|Tg(Sftpc-cre)1Blh

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• bronchial epithelial hyperplasia
  http://purl.obolibrary.org/obo/MP_0005488

文献

http://purl.org/net/cito/citesAsAuthority

• Yun. Lu, et.al., Evidence that SOX2 overexpression is oncogenic in the lung., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20548776