pancreatic islet hyperplasia_Kdm5a<tm1Kael>/Kdm5a<tm1Kael>,Men1<tm2.1Mmey>/Men1<tm2.1Mmey>,Tg(Ins2-cre)23Herr/0

http://metadb.riken.jp/0005491I129S6SvEvTacC57BL6CBAJFVBNKdm5atm1KaelKdm5atm1KaelMen1tm21MmeyMen1tm21MmeyTgIns2cre23Herr0Kdm5atm1KaelTgIns2cre23HerrMen1tm21Mmey

pancreatic islet hyperplasia_Kdm5a<tm1Kael>/Kdm5a<tm1Kael>,Men1<tm2.1Mmey>/Men1<tm2.1Mmey>,Tg(Ins2-cre)23Herr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• multiple endocrine neoplasia 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316736
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238
• lysine (K)-specific demethylase 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136980

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kdm5a<tm1Kael>/Kdm5a<tm1Kael>,Men1<tm2.1Mmey>/Men1<tm2.1Mmey>,Tg(Ins2-cre)23Herr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kdm5a<tm1Kael>|Tg(Ins2-cre)23Herr|Men1<tm2.1Mmey>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA/J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• pancreatic islet hyperplasia
  http://purl.obolibrary.org/obo/MP_0005491

文献

http://purl.org/net/cito/citesAsAuthority

• Wenchu. Lin, et.al., Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21788502