increased bone mass_Htr1b<tm1Rhn>/Htr1b<+>,Tph1<tm1Kry>/Tph1<+>,Tg(Vil-cre)20Syr/0

http://metadb.riken.jp/0005605I129S2SvPasC57BL6DBA2Htr1btm1RhnHtr1bTph1tm1KryTph1TgVilcre20Syr0Tph1tm1KryHtr1bHtr1btm1RhnTph1TgVilcre20Syr

increased bone mass_Htr1b<tm1Rhn>/Htr1b<+>,Tph1<tm1Kry>/Tph1<+>,Tg(Vil-cre)20Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 20, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053809
• tryptophan hydroxylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98796
• 5-hydroxytryptamine (serotonin) receptor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:96274

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Htr1b<tm1Rhn>/Htr1b<+>,Tph1<tm1Kry>/Tph1<+>,Tg(Vil-cre)20Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tph1<tm1Kry>|Htr1b<+>|Htr1b<tm1Rhn>|Tph1<+>|Tg(Vil-cre)20Syr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased bone mass
  http://purl.obolibrary.org/obo/MP_0005605

文献

http://purl.org/net/cito/citesAsAuthority

• Vijay K. Yadav, et.al., Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum., Cell, 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/19041748