decreased dopamine level_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0

http://metadb.riken.jp/0005643I129X1SvJC57BL6C57BL6JSJLSlc6a3tm2tTAXzSlc6a3TgtetOCOX8APstI1Ctm0Slc6a3Slc6a3tm2tTAXzTgtetOCOX8APstI1Ctm

decreased dopamine level_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862
• transgene insertion 1, Carlos T Moraes
  http://metadb.riken.jp/db/mgi_rdf/MGI:5315848

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<+>|Slc6a3<tm2(tTA)Xz>|Tg(tetO-COX8A/PstI*)1Ctm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopamine level
  http://purl.obolibrary.org/obo/MP_0005643

文献

http://purl.org/net/cito/citesAsAuthority

• Alicia M. Pickrell, et.al., Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/22131425