Alicia M. Pickrell, et.al., Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31

http://rdf.ncbi.nlm.nih.gov/pubmed/22131425

Alicia M. Pickrell, et.al., Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal substantia nigra morphology_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• abnormal striatum morphology_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
  http://metadb.riken.jp/0004077I129X1SvJC57BL6C57BL6JSJLSlc6a3tm2tTAXzSlc6a3TgtetOCOX8APstI1Ctm0Slc6a3Slc6a3tm2tTAXzTgtetOCOX8APstI1Ctm
• increased serotonin level_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• slow postnatal weight gain_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• abnormal noradrenaline level_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
  http://metadb.riken.jp/0003964I129X1SvJC57BL6C57BL6JSJLSlc6a3tm2tTAXzSlc6a3TgtetOCOX8APstI1Ctm0Slc6a3Slc6a3tm2tTAXzTgtetOCOX8APstI1Ctm
• decreased exploration in new environment_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• decreased dopamine level_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• abnormal synaptic bouton morphology_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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• impaired coordination_Slc6a3<tm2(tTA)Xz>/Slc6a3<+>,Tg(tetO-COX8A/PstI*)1Ctm/0
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