decreased dopamine level_Tg(PDGFB-LRRK2*R1441C)574Djmo/0

http://metadb.riken.jp/0005643IC3HHeJC57BL6JTgPDGFBLRRK2R1441C574Djmo0TgPDGFBLRRK2R1441C574Djmo

decreased dopamine level_Tg(PDGFB-LRRK2*R1441C)574Djmo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 574, Darren Moore
  http://metadb.riken.jp/db/mgi_rdf/MGI:4950681

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(PDGFB-LRRK2*R1441C)574Djmo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PDGFB-LRRK2*R1441C)574Djmo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopamine level
  http://purl.obolibrary.org/obo/MP_0005643

文献

http://purl.org/net/cito/citesAsAuthority

• David. Ramonet, et.al., Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21494637