decreased circulating leptin level_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>

http://metadb.riken.jp/0005668IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita

decreased circulating leptin level_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin II
  http://metadb.riken.jp/db/mgi_rdf/MGI:96573
• ring finger protein 213
  http://metadb.riken.jp/db/mgi_rdf/MGI:1289196

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rnf213<tm1.1Akoi>|Ins2<+>|Ins2<Akita>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * C57BL/6NSlc

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating leptin level
  http://purl.obolibrary.org/obo/MP_0005668

文献

http://purl.org/net/cito/citesAsAuthority

• Hatasu. Kobayashi, et.al., Ablation of Rnf213 retards progression of diabetes in the Akita mouse., Biochemical and biophysical research communications, 2013, 432
  http://rdf.ncbi.nlm.nih.gov/pubmed/23410753