Hatasu. Kobayashi, et.al., Ablation of Rnf213 retards progression of diabetes in the Akita mouse., Biochemical and biophysical research communications, 2013, 432

http://rdf.ncbi.nlm.nih.gov/pubmed/23410753

Hatasu. Kobayashi, et.al., Ablation of Rnf213 retards progression of diabetes in the Akita mouse., Biochemical and biophysical research communications, 2013, 432

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5510405

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating glucose level_Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0005560IC57BL6NRnf213tm11AkoiRnf213tm11AkoiRnf213tm11Akoi
• abnormal pancreatic islet morphology_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0005215IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• decreased insulin secretion_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0003059IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• decreased circulating leptin level_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0005668IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• decreased body weight_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0001262IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• abnormal pancreatic islet morphology_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0005215IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• increased circulating glucose level_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0005559IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• increased food intake_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0011939IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• increased circulating glucose level_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0005559IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• decreased body weight_Ins2<Akita>/Ins2<+>
  http://metadb.riken.jp/0001262IC57BL6NSlcIns2AkitaIns2Ins2AkitaIns2
• decreased insulin secretion_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0003059IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• decreased insulin secretion_Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0003059IC57BL6NRnf213tm11AkoiRnf213tm11AkoiRnf213tm11Akoi
• decreased pancreatic beta cell number_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0003339IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• increased food intake_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0011939IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• impaired glucose tolerance_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0005293IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita
• decreased body weight_Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0001262IC57BL6NRnf213tm11AkoiRnf213tm11AkoiRnf213tm11Akoi
• decreased circulating leptin level_Ins2<Akita>/Ins2<+>,Rnf213<tm1.1Akoi>/Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/0005668IC57BL6NC57BL6NSlcIns2AkitaIns2Rnf213tm11AkoiRnf213tm11AkoiRnf213tm11AkoiIns2Ins2Akita

class

http://purl.org/net/cito/citesAsAuthority

• Rnf213<tm1.1Akoi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5510405

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating leptin level in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004833
• increased food intake in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014272
• decreased insulin secretion in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014247
• abnormal pancreatic islet morphology in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014249
• decreased body weight in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011688
• increased circulating glucose level in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004832
• abnormal pancreatic islet morphology in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004824
• decreased body weight in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014231
• homeostasis/metabolism phenotype in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015728
• decreased insulin secretion in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1011705
• increased food intake in RBRC02661
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010579
• decreased circulating leptin level in RBRC02659
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014257