increased circulating leptin level_Lepr<tm1.2Chua>/Lepr<tm1.2Chua>,Nos1<tm1(cre)Mgmj>/Nos1<+>

http://metadb.riken.jp/0005669I129S1Sv129X1SvJC57BL6Leprtm12ChuaLeprtm12ChuaNos1tm1creMgmjNos1Nos1tm1creMgmjNos1Leprtm12Chua

increased circulating leptin level_Lepr<tm1.2Chua>/Lepr<tm1.2Chua>,Nos1<tm1(cre)Mgmj>/Nos1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993
• nitric oxide synthase 1, neuronal
  http://metadb.riken.jp/db/mgi_rdf/MGI:97360

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<tm1.2Chua>/Lepr<tm1.2Chua>,Nos1<tm1(cre)Mgmj>/Nos1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nos1<tm1(cre)Mgmj>|Nos1<+>|Lepr<tm1.2Chua>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating leptin level
  http://purl.obolibrary.org/obo/MP_0005669

文献

http://purl.org/net/cito/citesAsAuthority

• Rebecca L. Leshan, et.al., Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance., Nature medicine, 2012, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/22522563