decreased apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0006043I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd

decreased apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased apoptosis
  http://purl.obolibrary.org/obo/MP_0006043

文献

http://purl.org/net/cito/citesAsAuthority

• Hoseok. Song, et.al., p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM., Nature cell biology, 2007, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/17417627
• A U. Zaidi, et.al., Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11150333
• Franck. Toledo, et.al., A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network., Cancer cell, 2006, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/16616333