abnormal retinal neuronal layer morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

http://metadb.riken.jp/0006069I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc

abnormal retinal neuronal layer morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr2<tm1.2Hlm>|Tg(CAG-cre/Esr1*)5Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal neuronal layer morphology
  http://purl.obolibrary.org/obo/MP_0006069

文献

http://purl.org/net/cito/citesAsAuthority

• Barbara M. Braunger, et.al., Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy., The American journal of pathology, 2015, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/25857227