Barbara M. Braunger, et.al., Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy., The American journal of pathology, 2015, 185

http://rdf.ncbi.nlm.nih.gov/pubmed/25857227

Barbara M. Braunger, et.al., Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy., The American journal of pathology, 2015, 185

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microgliosis_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0008918I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• thin retinal outer nuclear layer_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0008515I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• retina microaneurysm_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0010452I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• persistence of hyaloid vascular system_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0001289I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• retinal detachment_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0003099I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• decreased b wave amplitude_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0012144I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• increased retinal apoptosis_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0030005I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal retinal blood vessel morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0010097I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal retinal vasculature morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0002792I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal retina morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0001325I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• decreased a wave amplitude_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0012143I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal pericyte morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0003719I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• hypoxia_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0005039I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal electroretinogram waveform feature_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0012029I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal retinal neuronal layer morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0006069I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• decreased retinal ganglion cell number_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0006309I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• vitreous body hemorrhage_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0006202I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• retinal hemorrhage_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0006185I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• abnormal retinal layer morphology_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0003727I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc
• retinal neovascularization_Tg(CAG-cre/Esr1*)5Amc/0,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>
  http://metadb.riken.jp/0008852I129S6SvEvTacC57BL6CBATgCAGcreEsr15Amc0Tgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmTgCAGcreEsr15Amc