abnormal cardiac outflow tract development_Fgf8<tm1.3Mrt>/Fgf8<+>,Six1<tm1(cre,ALPP)Xli>/Six1<+>

http://metadb.riken.jp/0006126I129129P2OlaHsdC57BL6Fgf8tm13MrtFgf8Six1tm1creALPPXliSix1Six1tm1creALPPXliFgf8Six1Fgf8tm13Mrt

abnormal cardiac outflow tract development_Fgf8<tm1.3Mrt>/Fgf8<+>,Six1<tm1(cre,ALPP)Xli>/Six1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• sine oculis-related homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102780

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1.3Mrt>/Fgf8<+>,Six1<tm1(cre,ALPP)Xli>/Six1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Six1<tm1(cre,ALPP)Xli>|Fgf8<+>|Six1<+>|Fgf8<tm1.3Mrt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal outflow tract development
  http://purl.obolibrary.org/obo/MP_0006126

文献

http://purl.org/net/cito/citesAsAuthority

• Chaoshe. Guo, et.al., A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21364285