congestive heart failure_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0

http://metadb.riken.jp/0006138I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf

congestive heart failure_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chloride channel, voltage-sensitive 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103555
• transgene insertion 3, Jeffrey I Gordon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3041442
• transgene insertion 6, Section of Myocardial Biology - Fishman Lab
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665552

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Clcn3<tm1.1Jrhm>|Tg(tetO-cre)3Jig|Tg(Myh6-tTA)6Smbf

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• congestive heart failure
  http://purl.obolibrary.org/obo/MP_0006138

文献

http://purl.org/net/cito/citesAsAuthority

• Dazhi. Xiong, et.al., Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice., Journal of molecular and cellular cardiology, 2010, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/19615374