Dazhi. Xiong, et.al., Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice., Journal of molecular and cellular cardiology, 2010, 48

http://rdf.ncbi.nlm.nih.gov/pubmed/19615374

Dazhi. Xiong, et.al., Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice., Journal of molecular and cellular cardiology, 2010, 48

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Clcn3<tm1Jrhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699053
• Clcn3<tm1.1Jrhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699055

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart echocardiography feature_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0011925I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• enlarged heart_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0000274I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• premature death_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• increased heart weight_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0002833I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• myocardial hypertrophy_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0010633I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• dilated cardiomyopathy_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0002795I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• decreased ventricle muscle contractility_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0005598I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• congestive heart failure_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0006138I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf
• abnormal myocardial fiber physiology_Clcn3<tm1.1Jrhm>/Clcn3<tm1.1Jrhm>,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
  http://metadb.riken.jp/0004215I129S1Sv129X1SvJC57BL6JFVBNClcn3tm11JrhmClcn3tm11JrhmTgMyh6tTA6Smbf0TgtetOcre3Jig0Clcn3tm11JrhmTgtetOcre3JigTgMyh6tTA6Smbf

class

http://purl.org/net/cito/citesAsAuthority

• Clcn3<tm1Jrhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699053
• Clcn3<tm1.1Jrhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699055