increased medulloblastoma incidence_Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols

http://metadb.riken.jp/0006283C57BL6TgNeurod2SmoA1199JolsTgNeurod2SmoA1199JolsTgNeurod2SmoA1199JolsTgNeurod2SmoA1199Jols

increased medulloblastoma incidence_Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 199, James M Olson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830736

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Neurod2-Smo*A1)199Jols

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C57BL/6-Tg(Neurod2-Smo*A1)199Jols

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Beryl A. Hatton, et.al., The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread., Cancer research, 2008, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/18339857
• Joyoti. Dey, et.al., A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model., Molecular and cellular biology, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22869526