increased medulloblastoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0

http://metadb.riken.jp/0006283I129P2OlaHsdPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgNescreERT2ALPP1Sbk0Ptentm2MakTrp53tm1BrnTgNescreERT2ALPP1Sbk

increased medulloblastoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Suzanne J Baker
  http://metadb.riken.jp/db/mgi_rdf/MGI:5304275
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm2Mak>|Trp53<tm1Brn>|Tg(Nes-cre/ERT2,-ALPP)1Sbk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Guo. Zhu, et.al., PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation., Cancer research, 2017, 77
  http://rdf.ncbi.nlm.nih.gov/pubmed/27815386