increased medulloblastoma incidence_Xrcc1<tm1Pmc>/Xrcc1<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6SJLXrcc1tm1PmcXrcc1tm1PmcTrp53tm1TyjTrp53TgNescre1Kln0Trp53Trp53tm1TyjXrcc1tm1PmcTgNescre1Kln

increased medulloblastoma incidence_Xrcc1<tm1Pmc>/Xrcc1<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• X-ray repair complementing defective repair in Chinese hamster cells 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99137
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Xrcc1<tm1Pmc>/Xrcc1<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm1Tyj>|Xrcc1<tm1Pmc>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Youngsoo. Lee, et.al., The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1., Nature neuroscience, 2009, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/19633665