increased medulloblastoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>

http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj

increased medulloblastoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• X-ray repair complementing defective repair in Chinese hamster cells 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927345
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Xrcc2<tm1Pmc>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Kenji E. Orii, et.al., Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16777961