increased medulloblastoma incidence_Ptch1<tm1Mps>/Ptch1<+>

http://metadb.riken.jp/0006283I129S1Sv129X1SvJPtch1tm1MpsPtch1Ptch1tm1MpsPtch1

increased medulloblastoma incidence_Ptch1<tm1Mps>/Ptch1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptch1<tm1Mps>/Ptch1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptch1<tm1Mps>|Ptch1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Junhao. Mao, et.al., A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway., Cancer research, 2006, 66
  http://rdf.ncbi.nlm.nih.gov/pubmed/17047082
• Tracy-Ann. Read, et.al., Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19185848
• Tamar. Uziel, et.al., The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16260494