Junhao. Mao, et.al., A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway., Cancer research, 2006, 66

http://rdf.ncbi.nlm.nih.gov/pubmed/17047082

Junhao. Mao, et.al., A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway., Cancer research, 2006, 66

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0006283I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• intestine polyps_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0008011I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• increased basal cell carcinoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0004208I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• increased rhabdomyosarcoma incidence_Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0002036I129S1Sv129X1SvJPtch1tm1MpsPtch1Ptch1tm1MpsPtch1
• premature death_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0002083I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• increased rhabdomyosarcoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0002036I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• gastric polyps_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0003299I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc
• increased medulloblastoma incidence_Ptch1<tm1Mps>/Ptch1<+>
  http://metadb.riken.jp/0006283I129S1Sv129X1SvJPtch1tm1MpsPtch1Ptch1tm1MpsPtch1
• abnormal pancreas morphology_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/?,Tg(CAG-cre/Esr1*)5Amc/?
  http://metadb.riken.jp/0001944I129X1SvJC57BL6CBAGtROSA26Sortm1SmoEYFPAmcTgCAGcreEsr15AmcTgCAGcreEsr15AmcGtROSA26Sortm1SmoEYFPAmc

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased rhabdomyosarcoma incidence in RBRC06251
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017516
• increased medulloblastoma incidence in RBRC06251
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017519