increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0

http://metadb.riken.jp/0006283I129X1SvJFVBNGtROSA26Sortm1SmoEYFPAmcGtROSA26Sortm1SmoEYFPAmcTgAtoh1creEsr114Fsh0TgAtoh1creEsr114FshGtROSA26Sortm1SmoEYFPAmc

increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 14, Gordon Fishell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3615689
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>/Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>,Tg(Atoh1-cre/Esr1*)14Fsh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Atoh1-cre/Esr1*)14Fsh|Gt(ROSA)26Sor<tm1(Smo/EYFP)Amc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Ulrich. Schüller, et.al., Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18691547