abnormal retinal nerve fiber layer morphology_Tspan12<tm1Wye>/Tspan12<tm1Wye>

http://metadb.riken.jp/0006303EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye

abnormal retinal nerve fiber layer morphology_Tspan12<tm1Wye>/Tspan12<tm1Wye>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tetraspanin 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889818

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tspan12<tm1Wye>/Tspan12<tm1Wye>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tspan12<tm1Wye>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: B6.129S5-Tspan12<tm1Wye> or FVB.129S5-Tspan12<tm1Wye>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal nerve fiber layer morphology
  http://purl.obolibrary.org/obo/MP_0006303

文献

http://purl.org/net/cito/citesAsAuthority

• Harald J. Junge, et.al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling., Cell, 2009, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19837033