Harald J. Junge, et.al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling., Cell, 2009, 139

http://rdf.ncbi.nlm.nih.gov/pubmed/19837033

Harald J. Junge, et.al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling., Cell, 2009, 139

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tspan12<tm1Wye>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414643
• Ndp<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414644

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased vascular permeability_Ndp<tm1Lex>/Y
  http://metadb.riken.jp/0003070I129S5SvEvBrdNdptm1LexYNdptm1Lex
• vasculature congestion_Ndp<tm1Lex>/Y
  http://metadb.riken.jp/0000255I129S5SvEvBrdNdptm1LexYNdptm1Lex
• persistence of hyaloid vascular system_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0001289EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• retinal gliosis_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0009392EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• abnormal retinal vasculature morphology_Lrp5<Gt(OST164883)Lex>/Lrp5<Gt(OST164883)Lex>
  http://metadb.riken.jp/0002792I129S5SvEvBrdLrp5GtOST164883LexLrp5GtOST164883LexLrp5GtOST164883Lex
• abnormal retinal vasculature morphology_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0002792EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• abnormal retinal nerve fiber layer morphology_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0006303EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• retinal hemorrhage_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0006185EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• abnormal retinal vasculature morphology_Ndp<tm1Lex>/Ndp<tm1Lex>
  http://metadb.riken.jp/0002792I129S5SvEvBrdNdptm1LexNdptm1LexNdptm1Lex
• abnormal retinal vasculature morphology_Lrp5<Gt(OST164883)Lex>/Lrp5<+>,Tspan12<tm1Wye>/Tspan12<+>
  http://metadb.riken.jp/0002792EI129S5SvEvBrdC57BL6orI129S5SvEvBrdFVBNLrp5GtOST164883LexLrp5Tspan12tm1WyeTspan12Tspan12tm1WyeLrp5GtOST164883LexLrp5Tspan12
• vasculature congestion_Lrp5<Gt(OST164883)Lex>/Lrp5<Gt(OST164883)Lex>
  http://metadb.riken.jp/0000255I129S5SvEvBrdLrp5GtOST164883LexLrp5GtOST164883LexLrp5GtOST164883Lex
• thin retinal outer nuclear layer_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0008515EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• abnormal retinal vasculature morphology_Ndp<tm1Lex>/Y,Tspan12<tm1Wye>/Tspan12<+>
  http://metadb.riken.jp/0002792EI129S5SvEvBrdC57BL6orI129S5SvEvBrdFVBNNdptm1LexYTspan12tm1WyeTspan12Tspan12Ndptm1LexTspan12tm1Wye
• retina microaneurysm_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0010452EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• abnormal retinal vasculature morphology_Tspan12<tm1Wye>/Tspan12<+>
  http://metadb.riken.jp/0002792EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12Tspan12Tspan12tm1Wye
• abnormal retinal vasculature morphology_Ndp<tm1Lex>/Ndp<tm1Lex>,Tspan12<tm1Wye>/Tspan12<+>
  http://metadb.riken.jp/0002792EI129S5SvEvBrdC57BL6orI129S5SvEvBrdFVBNNdptm1LexNdptm1LexTspan12tm1WyeTspan12Tspan12Ndptm1LexTspan12tm1Wye
• abnormal stria vascularis vasculature morphology_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0004368EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye
• increased vascular permeability_Ndp<tm1Lex>/Ndp<tm1Lex>
  http://metadb.riken.jp/0003070I129S5SvEvBrdNdptm1LexNdptm1LexNdptm1Lex
• abnormal retinal vasculature morphology_Ndp<tm1Lex>/Y
  http://metadb.riken.jp/0002792I129S5SvEvBrdNdptm1LexYNdptm1Lex
• vasculature congestion_Ndp<tm1Lex>/Ndp<tm1Lex>
  http://metadb.riken.jp/0000255I129S5SvEvBrdNdptm1LexNdptm1LexNdptm1Lex
• increased vascular permeability_Lrp5<Gt(OST164883)Lex>/Lrp5<Gt(OST164883)Lex>
  http://metadb.riken.jp/0003070I129S5SvEvBrdLrp5GtOST164883LexLrp5GtOST164883LexLrp5GtOST164883Lex
• vasculature congestion_Tspan12<tm1Wye>/Tspan12<tm1Wye>
  http://metadb.riken.jp/0000255EB6129S5Tspan12tm1WyeorFVB129S5Tspan12tm1WyeTspan12tm1WyeTspan12tm1WyeTspan12tm1Wye

class

http://purl.org/net/cito/citesAsAuthority

• Tspan12<tm1Wye>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414643
• Ndp<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414644

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD17061
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17061
• CD12277
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12277
• CD43621
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD43621