increased myocardial fiber number_Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/A1cf<+>

http://metadb.riken.jp/0006321I129C57BL6FVBNGtROSA26Sortm11CAGMirc20EemGtROSA26SorA1cfTgMyh6creEsr11JmkA1cfA1cfTgMyh6creEsr11JmkA1cfGtROSA26SorGtROSA26Sortm11CAGMirc20Eem

increased myocardial fiber number_Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/A1cf<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• APOBEC1 complementation factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917115
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/A1cf<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• A1cf<Tg(Myh6-cre/Esr1*)1Jmk>|A1cf<+>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased myocardial fiber number
  http://purl.obolibrary.org/obo/MP_0006321

文献

http://purl.org/net/cito/citesAsAuthority

• Ying. Tian, et.al., A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice., Science translational medicine, 2015, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/25787764