increased T cell apoptosis_Akt1<tm1Pnt>/Akt1<tm1Pnt>,Akt2<tm1.1Mbb>/Akt2<tm1.1Mbb>,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0006413I129P2OlaHsdAkt1tm1PntAkt1tm1PntAkt2tm11MbbAkt2tm11MbbTgLckcre1Cwi0Akt2tm11MbbAkt1tm1PntTgLckcre1Cwi

increased T cell apoptosis_Akt1<tm1Pnt>/Akt1<tm1Pnt>,Akt2<tm1.1Mbb>/Akt2<tm1.1Mbb>,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thymoma viral proto-oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87986
• thymoma viral proto-oncogene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104874
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Akt1<tm1Pnt>/Akt1<tm1Pnt>,Akt2<tm1.1Mbb>/Akt2<tm1.1Mbb>,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Akt2<tm1.1Mbb>|Akt1<tm1Pnt>|Tg(Lck-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell apoptosis
  http://purl.obolibrary.org/obo/MP_0006413

文献

http://purl.org/net/cito/citesAsAuthority

• Changchuin. Mao, et.al., Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition., Journal of immunology (Baltimore, Md. : 1950), 2007, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/17442925