increased T cell apoptosis_Brca2<tm1Mak>/Brca2<tm2Mak>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0006413I129P2OlaHsdC57BL6CBABrca2tm1MakBrca2tm2MakTgLckcre548Jxm0Brca2tm1MakTgLckcre548JxmBrca2tm2Mak

increased T cell apoptosis_Brca2<tm1Mak>/Brca2<tm2Mak>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• breast cancer 2, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:109337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca2<tm1Mak>/Brca2<tm2Mak>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca2<tm1Mak>|Tg(Lck-cre)548Jxm|Brca2<tm2Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell apoptosis
  http://purl.obolibrary.org/obo/MP_0006413

文献

http://purl.org/net/cito/citesAsAuthority

• Alison M Y. Cheung, et.al., Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis., Cancer research, 2002, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/12414647