early cellular replicative senescence_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>

http://metadb.riken.jp/0008008I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd

early cellular replicative senescence_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• BUB1, mitotic checkpoint serine/threonine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100510

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bub1<tm1.1Tvd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Mark. Schliekelman, et.al., Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19117986