Mark. Schliekelman, et.al., Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis., Cancer research, 2009, 69

http://rdf.ncbi.nlm.nih.gov/pubmed/19117986

Mark. Schliekelman, et.al., Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis., Cancer research, 2009, 69

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bub1<tm1Tvd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830858
• Bub1<tm1.1Tvd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830859
• Bub1<Gt(XG453)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830862

class

http://purl.org/net/cito/citesAsAuthority

• Bub1<tm1Tvd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830858
• Bub1<tm1.1Tvd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830859
• Bub1<Gt(XG453)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3830862

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased leukocyte cell number_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0000218B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• pale liver_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0000603B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• anemia_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0001577B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• hepatic necrosis_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0001654B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• increased incidence of induced tumors_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0002021I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• no abnormal phenotype detected_Bub1<tm1Tvd>/Bub1<+>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6JBub1tm1TvdBub1Bub1tm1TvdBub1
他17件を見る
• abnormal cell cycle_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0003077I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• maternal effect_Bub1<Gt(XG453)Byg>/Bub1<+>
  http://metadb.riken.jp/0003718I129P2OlaHsdC57BL6JBub1GtXG453BygBub1Bub1GtXG453BygBub1
• aneuploidy_Bub1<tm1.1Tvd>/Bub1<+>
  http://metadb.riken.jp/0004024I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1Bub1Bub1tm11Tvd
• aneuploidy_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0004024I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• abnormal cell cycle checkpoint function_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0004045I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• early cellular replicative senescence_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0008008I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• increased lung tumor incidence_Bub1<tm1.1Tvd>/Bub1<+>
  http://metadb.riken.jp/0008014I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1Bub1Bub1tm11Tvd
• increased lung tumor incidence_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0008014I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• increased liver tumor incidence_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0008019I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• increased brain tumor incidence_Bub1<tm1.1Tvd>/Bub1<+>
  http://metadb.riken.jp/0009277I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1Bub1Bub1tm11Tvd
• decreased birth weight_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0009674B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• abnormal mitotic spindle morphology_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0009760I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• abnormal mitotic spindle assembly checkpoint_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0009762I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• perinatal lethality, incomplete penetrance_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0011090B6129P2Bub1tm11TvdBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• perinatal lethality, incomplete penetrance_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0011090I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd
• embryonic lethality during organogenesis, complete penetrance_Bub1<Gt(XG453)Byg>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JBub1GtXG453BygBub1tm11TvdBub1GtXG453BygBub1tm11Tvd
• decreased fibroblast proliferation_Bub1<tm1.1Tvd>/Bub1<tm1.1Tvd>
  http://metadb.riken.jp/0011704I129P2OlaHsd129S7SvEvBrdC57BL6JBub1tm11TvdBub1tm11TvdBub1tm11Tvd