early cellular replicative senescence_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>

http://metadb.riken.jp/0008008I129S4SvJae129S6SvEvTacC57BL6Cdkn1atm1LedCdkn1atm1LedHdac2tm12RdpHdac2tm12RdpCdkn1atm1LedHdac2tm12Rdp

early cellular replicative senescence_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histone deacetylase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097691
• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Led>|Hdac2<tm1.2Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Roel H. Wilting, et.al., Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20571512