early cellular replicative senescence_Tg(KRT5-cre/PGR)1Der/0,Trp63<tm2Brd>/Trp63<tm3.1Brd>

http://metadb.riken.jp/0008008I129S7SvEvBrdFVBICRTgKRT5crePGR1Der0Trp63tm2BrdTrp63tm31BrdTrp63tm31BrdTrp63tm2BrdTgKRT5crePGR1Der

early cellular replicative senescence_Tg(KRT5-cre/PGR)1Der/0,Trp63<tm2Brd>/Trp63<tm3.1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Dennis R Roop
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651407
• transformation related protein 63
  http://metadb.riken.jp/db/mgi_rdf/MGI:1330810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(KRT5-cre/PGR)1Der/0,Trp63<tm2Brd>/Trp63<tm3.1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp63<tm3.1Brd>|Trp63<tm2Brd>|Tg(KRT5-cre/PGR)1Der

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• William M. Keyes, et.al., p63 deficiency activates a program of cellular senescence and leads to accelerated aging., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16107615