early cellular replicative senescence_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0008008IC57BL6CBASJLCdk1tm21KaldCdk1tm21KaldTgCAGcreEsr15Amc0Cdk1tm21KaldTgCAGcreEsr15Amc

early cellular replicative senescence_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• cyclin-dependent kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88351

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk1<tm2.1Kald>|Tg(CAG-cre/Esr1*)5Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• M Kasim. Diril, et.al., Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22355113