M Kasim. Diril, et.al., Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22355113

M Kasim. Diril, et.al., Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk1<tm2.1Kald>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5318085
• Cdk1<tm2.2Kald>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5318086

class

http://purl.org/net/cito/citesAsAuthority

• Cdk1<tm2.1Kald>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5318085
• Cdk1<tm2.2Kald>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5318086

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• polyploidy_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004025IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• abnormal blastocyst morphology_Cdk1<tm2.2Kald>/Cdk1<tm2.2Kald>
  http://metadb.riken.jp/0004957IC57BL6FVBNSJLCdk1tm22KaldCdk1tm22KaldCdk1tm22Kald
• embryonic lethality, complete penetrance_Cdk1<tm2.2Kald>/Cdk1<tm2.2Kald>
  http://metadb.riken.jp/0011092IC57BL6FVBNSJLCdk1tm22KaldCdk1tm22KaldCdk1tm22Kald
• decreased tumor growth/size_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003447IC57BL6CBASJLCdk1tm21KaldCdk1tm21KaldTgCAGcreEsr15Amc0Cdk1tm21KaldTgCAGcreEsr15Amc
• early cellular replicative senescence_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008008IC57BL6CBASJLCdk1tm21KaldCdk1tm21KaldTgCAGcreEsr15Amc0Cdk1tm21KaldTgCAGcreEsr15Amc
• abnormal cell nucleus count_Cdk1<tm2.2Kald>/Cdk1<tm2.2Kald>
  http://metadb.riken.jp/0003706IC57BL6FVBNSJLCdk1tm22KaldCdk1tm22KaldCdk1tm22Kald
• failure of zygotic cell division_Cdk1<tm2.2Kald>/Cdk1<tm2.2Kald>
  http://metadb.riken.jp/0003406IC57BL6FVBNSJLCdk1tm22KaldCdk1tm22KaldCdk1tm22Kald
• abnormal mitosis_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004046IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• decreased cell proliferation_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000352IC57BL6CBASJLCdk1tm21KaldCdk1tm21KaldTgCAGcreEsr15Amc0Cdk1tm21KaldTgCAGcreEsr15Amc
• decreased hepatocyte proliferation_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004001IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• decreased incidence of induced tumors_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002053IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• abnormal response to injury_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005164IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• abnormal DNA replication_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008057IC57BL6CBASJLCdk1tm21KaldCdk1tm21KaldTgCAGcreEsr15Amc0Cdk1tm21KaldTgCAGcreEsr15Amc
• decreased hepatocyte number_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000606IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• abnormal hepatocyte morphology_Cdk1<tm2.1Kald>/Cdk1<tm2.1Kald>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000607IC57BL6DBASJLCdk1tm21KaldCdk1tm21KaldTgAlbcre21Mgn0TgAlbcre21MgnCdk1tm21Kald
• abnormal cell nucleus morphology_Cdk1<tm2.2Kald>/Cdk1<tm2.2Kald>
  http://metadb.riken.jp/0003111IC57BL6FVBNSJLCdk1tm22KaldCdk1tm22KaldCdk1tm22Kald