increased lung tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

http://metadb.riken.jp/0008014I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm2NbrMapk14Polr2atm1creERT2BbdPolr2aKrastm1BbdPolr2atm1creERT2BbdKrasMapk14Polr2aMapk14tm2Nbr

increased lung tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• mitogen-activated protein kinase 14
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346865
• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm1Bbd>|Polr2a<tm1(cre/ERT2)Bbd>|Kras<+>|Mapk14<+>|Polr2a<+>|Mapk14<tm2Nbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung tumor incidence
  http://purl.obolibrary.org/obo/MP_0008014

文献

http://purl.org/net/cito/citesAsAuthority

• Juan José. Ventura, et.al., p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation., Nature genetics, 2007, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/17468755