increased lung tumor incidence_Kras<tm4Tyj>/Kras<+>,Mapk8<tm1Wag>/Mapk8<+>,Mapk9<tm1Mka>/Mapk9<tm1Mka>

http://metadb.riken.jp/0008014I129Sv129P2OlaHsd129S4SvJaeC57BL6Krastm4TyjKrasMapk8tm1WagMapk8Mapk9tm1MkaMapk9tm1MkaMapk8tm1WagMapk8KrasKrastm4TyjMapk9tm1Mka

increased lung tumor incidence_Kras<tm4Tyj>/Kras<+>,Mapk8<tm1Wag>/Mapk8<+>,Mapk9<tm1Mka>/Mapk9<tm1Mka>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346862
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• mitogen-activated protein kinase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346861

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Mapk8<tm1Wag>/Mapk8<+>,Mapk9<tm1Mka>/Mapk9<tm1Mka>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk8<tm1Wag>|Mapk8<+>|Kras<+>|Kras<tm4Tyj>|Mapk9<tm1Mka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung tumor incidence
  http://purl.obolibrary.org/obo/MP_0008014

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel. Schramek, et.al., The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression., Nature genetics, 2011, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/21317887