increased liver tumor incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0008019I129S6SvEvTacC57BL6CBACD1SJLSav1tm11RjoSav1tm11RjoTgCAGcreEsr15Amc0Sav1tm11RjoTgCAGcreEsr15Amc

increased liver tumor incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• salvador family WW domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927144

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sav1<tm1.1Rjo>|Tg(CAG-cre/Esr1*)5Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA * CD-1 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver tumor incidence
  http://purl.obolibrary.org/obo/MP_0008019

文献

http://purl.org/net/cito/citesAsAuthority

• Li. Lu, et.al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080689