increased liver tumor incidence_Pinx1<tm1.1Kplu>/Pinx1<+>,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0008019I129S7SvEvBrdC57BL6FVBNPinx1tm11KpluPinx1Trp53tm1BrdTrp53Pinx1Trp53tm1BrdTrp53Pinx1tm11Kplu

increased liver tumor incidence_Pinx1<tm1.1Kplu>/Pinx1<+>,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• PIN2/TERF1 interacting, telomerase inhibitor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919650
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pinx1<tm1.1Kplu>/Pinx1<+>,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pinx1<+>|Trp53<tm1Brd>|Trp53<+>|Pinx1<tm1.1Kplu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver tumor incidence
  http://purl.obolibrary.org/obo/MP_0008019

文献

http://purl.org/net/cito/citesAsAuthority

• Xiao Zhen. Zhou, et.al., The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21436583