increased CD4-positive, alpha beta T cell number_Foxo1<tm1Flv>/Foxo1<tm1Flv>,Ifng<tm1Ts>/Ifng<tm1Ts>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

http://metadb.riken.jp/0008074I129S1Sv129S6SvEvTac129S7SvEvBrd129X1SvJFoxo1tm1FlvFoxo1tm1FlvIfngtm1TsIfngtm1TsFoxp3tm4YFPicreAyrFoxp3Foxo1tm1FlvIfngtm1TsFoxp3Foxp3tm4YFPicreAyr

increased CD4-positive, alpha beta T cell number_Foxo1<tm1Flv>/Foxo1<tm1Flv>,Ifng<tm1Ts>/Ifng<tm1Ts>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077
• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• interferon gamma
  http://metadb.riken.jp/db/mgi_rdf/MGI:107656

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Flv>/Foxo1<tm1Flv>,Ifng<tm1Ts>/Ifng<tm1Ts>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxo1<tm1Flv>|Ifng<tm1Ts>|Foxp3<+>|Foxp3<tm4(YFP/icre)Ayr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008074

文献

http://purl.org/net/cito/citesAsAuthority

• Weiming. Ouyang, et.al., Novel Foxo1-dependent transcriptional programs control T(reg) cell function., Nature, 2012, 491
  http://rdf.ncbi.nlm.nih.gov/pubmed/23135404