decreased CD4-positive, alpha beta T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0008075I129C57BL6CBACrebbptm1JvdCrebbptm1JvdTgLckcre548Jxm0Crebbptm1JvdTgLckcre548Jxm

decreased CD4-positive, alpha beta T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CREB binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098280
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Crebbp<tm1Jvd>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Lawryn H. Kasper, et.al., Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16428436